Cell · 2019
TScan-I
A genome-scale method for identifying the antigens recognized by CD8+ T cells.
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Publications
Selected publications
Cell · 2023
TScan-II
A genome-scale platform for de novo identification of MHC class II-restricted CD4+ T-cell epitopes.
View publicationNature Biotechnology · 2024
TCR-MAP
Synthetic cellular circuits for high-throughput identification of MHC class I- and II-restricted T-cell epitopes.
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FULL PUBLICATION LIST
Human memory CD4+ T-cells recognize Mycobacterium tuberculosis-infected macrophages amid broader pathogen-specific responses
Volodymyr Stetsenko, Daniel P Gail, Scott Reba, Vinicius G Suzart, Avinaash K Sandhu, Alessandro Sette, Mohammad Haj Dezfulian, Cecilia S Lindestam Arlehamn, Stephen M Carpenter Journal of Experimental Medicine (2025)
GZMK+ CD8+ T Cells Target a Specific Acinar Cell Type in Sjögren’s Disease
Thomas J. F. Pranzatelli, Paola Perez, Anson Ku, Bruno Matuck, Khoa Huynh, Shunsuke Sakai, Mehdi Abed, Shyh-Ing Jang, Eiko Yamada, Kalie Dominick, Zara Ahmed, Amanda Oliver, Rachael Wasikowski, Quinn T. Easter, Alan N. Baer, Eileen Pelayo, Zohreh Khavandgar, David E. Kleiner, M. Teresa Magone, Sarthak Gupta, Christopher Lessard, A. Darise Farris, Peter D. Burbelo, Daniel Martin, Robert J. Morell, Changyu Zheng, Nicholas Rachmaninoff, Jose Maldonado-Ortiz, Xufeng Qu, Marit Aure, Mohammad Haj Dezfulian, Ross Lake, Sarah Teichmann, Daniel L. Barber, Lam C. Tsoi, Adam G. Sowalsky, Katarzyna M. Tyc, Jinze Liu, Johann Gudjonsson, Kevin M. Byrd, Philip L. F. Johnson, John A. Chiorini, Blake M. Warner, Annals of the Rheumatic Diseases (2025)
High-throughput discovery of MHC class I-and II-restricted T cell epitopes using synthetic cellular circuits
Ayano C Kohlgruber, Mohammad Haj Dezfulian, Brandon M Sie, Charlotte I Wang, Tomasz Kula, Uri Laserson, H Benjamin Larman, Stephen J Elledge Nature Biotechnology (2024)
TScan-II: A genome-scale platform for the de novo identification of CD4+ T cell epitopes
Mohammad Haj Dezfulian, Tomasz Kula, Thomas Pranzatelli, Nolan Kamitaki, Qingda Meng, Bhuwan Khatri, Paola Perez, Qikai Xu, Aiquan Chang, Ayano C Kohlgruber, Yumei Leng, Ananth Aditya Jupudi, Michelle L Joachims, John A Chiorini, Christopher J Lessard, A Darise Farris, Senthil K Muthuswamy, Blake M Warner, Stephen J Elledge Cell (2023)
* Featured in Nature Methods, Cell Reports Methods & Cancer Immunotherapy Research
Empirical identification and validation of tumor-targeting T cell receptors from circulation using autologous pancreatic tumor organoids
Qingda Meng, Shanshan Xie, G Kenneth Gray, Mohammad Haj Dezfulian, Omar Gandarilla, Weilin Li, Ling Huang, Dipikaa Akshinthala, Elizabeth Ferrer, Catherine Conahan, Sofia Perea Del Pino, Joseph Grossman, Stephen J Elledge, Manuel Hidalgo, Senthil K Muthuswamy. The Journal for ImmunoTherapy of Cancer (2021)
Integrated loss-and gain-of-function screens define a core network governing human embryonic stem cell behavior
Kamila Naxerova, Bruno Di Stefano, Jessica L Makofske, Emma V Watson, Marit A de Kort, Timothy D Martin, Mohammed Haj Dezfulian, Dominik Ricken, Eric C Wooten, Mitzi I Kuroda, Konrad Hochedlinger, Stephen J Elledge. Genes and Development (2021)
T-Scan: a genome-wide method for the systematic discovery of T cell epitopes
Tomasz Kula, Mohammad Haj Dezfulian, Charlotte I Wang, Nouran S Abdelfattah, Zachary C Hartman, Kai W Wucherpfennig, Herbert Kim Lyerly, Stephen J Elledge Cell (2019)
* Featured in Nature Methods, Trends in Immunology & Science Translational Medicine
Acetolactate synthase regulatory subunits play divergent and overlapping roles in branched-chain amino acid synthesis and Arabidopsis development
Mohammad Haj Dezfulian, Curtis Foreman, Espanta Jalili, Mrinal Pal, Rajdeep K Dhaliwal, Don Karl A Roberto, Kathleen M Imre, Susanne E Kohalmi, William L Crosby BMC Plant Biology (2017)
Oligomerization of SCFTIR1 Is Essential for Aux/IAA Degradation and Auxin Signaling in Arabidopsis
Mohammad Haj Dezfulian, Espanta Jalili, Don Karl A Roberto, Britney L Moss, Kerry Khoo, Jennifer L Nemhauser, William L Crosby, PLOS Genetics (2017)
In silico analyses of Wilms׳ tumor protein to designing a novel multi-epitope DNA vaccine against cancer
Saeed Khalili, Mohammad Reza Rahbar, Mohammad Haj Dezfulian, Abolfazl Jahangiri, Journal of Theoretical Biology (2015)
The SKP1-like gene family of Arabidopsis exhibits a high degree of differential gene expression and gene product interaction during development
Mohammad Haj Dezfulian, Danielle M Soulliere, Rajdeep K Dhaliwal, Madhulika Sareen, William L Crosby, PLOS One (2012)
Cheminformatics in anti-infective agents discovery
Soroush Sardari, Mohammad Haj Dezfulian, Mini Reviews in Medicinal Chemistry (2007)
PATENTS
Methods and compositions for identifying epitopes
Stephen Elledge, Tomasz Kula, Mohammad Haj Dezfulian (2018)