May 6, 2025 Website News ACR Convergence 2025Mo will be speaking at ACR Convergence 2025 in Chicago (Sunday, Oct 26) as part of the basic scienceRead More
May 5, 2025 Select Publications High-throughput discovery of MHC class I- and II-restricted T cell epitopes using synthetic cellular circuitsAntigen discovery technologies have largely focused on major histocompatibility complex (MHC) class I-restricted human T cell receptors (TCRs), leavingRead More
May 5, 2025 Select Publications T-Scan: A Genome-wide Method for the Systematic Discovery of T Cell EpitopesT cell recognition of specific antigens mediates protection from pathogens and controls neoplasias, but can also cause autoimmunity. OurRead More
May 5, 2025 Select Publications TScan-II: A genome-scale platform for the de novo identification of CD4+ T cell epitopes (Cell 2023) CD4+ T cells play fundamental roles in orchestrating immune responses and tissue homeostasis. However, our inability to associate peptide humanRead More
May 5, 2025 Select Publications High-throughput discovery of MHC class I- and II-restricted T cell epitopes using synthetic cellular circuits